CTX-1211

• Description:

  CTX-1211 is a selective, orally effective melanocortin MC4R agonist (EC50=0.38 nM) . CTX-1211 can enhance the feeding suppression and weight loss effects induced by liraglutide (HY-P0014), and promote anorexia and weight loss activity. CTX-1211 is mainly used in the study of obesity and other metabolic disorders[1].

• UNSPSC:

  12352209

• Target:

  Melanocortin Receptor

• Related Pathways:

  GPCR/G Protein; Neuronal Signaling

• Field of Research:

  Metabolic Disease

• Smiles:

  O=C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CSSC[C@@H](C(N)=O)NC1=O)C(N[C@@H](CC(O)=O)C(N[C@@H](C)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CC(O)=O)C(N[C@@H](CC2=CC=CC=C2)C(N[C@@H](CCCNC(N)=N)C(N[C@H]1CC3=CNC4=CC=CC=C34)=O)=O)=O)=O)=O)=O)=O)=O)C

• Molecular Formula:

  C57H83N21O15S2

• Molecular Weight:

  1366.53

• References & Citations:

  [1]Dahir NS, et al. Inhibition of the melanocortin-3 receptor (MC3R) causes generalized sensitization to anorectic agents. bioRxiv [Preprint]. 2023 Dec 7:2023.12.05.570114.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Peptides

• Clinical Information:

  No Development Reported

• Isoform:

  MC4R