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M-1211

CAT: 0804-HY-132234-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-132234-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
M 1121 is a covalent and orally active inhibitor of the menin-MLL interaction capable of achieving complete and persistent tumor regression[1].
CAS Number
2377337-93-2
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Epigenetic Reader Domain
Type
Reference compound
Related Pathways
Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/m-1211.html
Purity
99.29
Solubility
DMSO : 7.69 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
FC1=CC(C(CN2CCC2)([C@@]3([H])CCC[C@@H]3NC(OC)=O)C4CCN(CC5(OC)CN(C6=CC=C(S(N7C[C@@]8([H])N(C(C=C)=O)C[C@@]7(C8)[H])(=O)=O)C=C6)C5)CC4)=CC=C1
Molecular Formula
C42H57FN6O6S
Molecular Weight
793.00
Precautions
H302, H315, H319, H335
References & Citations
[1]Zhang M, et al. Discovery of M-1121 as an Orally Active Covalent Inhibitor of Menin-MLL Interaction Capable of Achieving Complete and Long-Lasting Tumor Regression. J Med Chem. 2021;64 (14) :10333-10349.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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