MI-1

• UNSPSC Description:

  MI-1 inhibits Menin-MLL interaction with an IC50 of 1.9 μM[1].

• Target Antigen:

  Epigenetic Reader Domain

• Type:

  Reference compound

• Related Pathways:

  Epigenetics

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/mi-1.html

• Solubility:

  10 mM in DMSO

• Smiles:

  CC1(C)CN=C(N2CCN(C3=C(C4=C(CCCC4)S5)C5=NC=N3)CC2)S1

• Molecular Weight:

  387.57

• References & Citations:

  [1]Vedadi M, et al. Targeting human SET1/MLL family of proteins. Protein Sci. 2017 Apr;26(4):662-676. doi: 10.1002/pro.3129. Epub 2017 Mar 6.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  433311-07-0