Products for Research Use Only
RegisterLogin

EGFR-IN-85

CAT: 0804-HY-111452Size: 1 EachDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-111452Size:1 Each
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
EGFR-IN-85 (Compound 1) is an EGFR inhibitor. EGFR-IN-85 has IC50 value of 0.19 μM for EGFRvIII phosphorylation. EGFR-IN-85 can suppress EGFR signaling within tumors. EGFR-IN-85 can be used for Glioblastoma (GBM) research[1].
CAS Number
1956378-29-2
UNSPSC
12352005
Target
EGFR
Type
Reference compound
Related Pathways
JAK/STAT Signaling; Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/egfr-in-85.html
Solubility
10 mM in DMSO
Smiles
O=C(NC1=CC(NC2=NC=CC(N3C=CC4=C3N=CC=C4)=N2)=C(C=C1N(CCN(C)C)C)OC)C=C
Molecular Formula
C26H30N8O2
Molecular Weight
486.57
References & Citations
[1]Zhao J, et al. (1h-pyrrolo[2,3-b]pyridin-1-yl) pyrimidin-2-yl-amino-phenyl--acrylamide inhibitors of egfr for use in the treatment of brain tumors. The United States, WO2022271861 A1. 2022-12-29.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Related Products

CatalogName
HY-141430-01AS-85
HY-179429NLRP3-IN-85
HY-178231ALK5-IN-85
HY-173035α-Glucosidase-IN-85
HY-19640AG-85
HY-173144AChE-IN-85
HY-170907HDAC-IN-85
HY-W127627Tween 85
HY-162212HSD17B13-IN-85
HY-117394-01MD 85

Alternative Products

CatalogName
T78574-01EGFR-IN-85
BA4870-10AS-85
FT47118-01Tween 85
MXC88557-01MNKI-85
TRC-L460000-10MGLisadimate (>85%)
T206359-01AChE-IN-85
442192BDE 85
TRC-P318095-10GPhenothrin (>85%)
TRC-B694370-250MGBusan 85
TRC-T910060-50MG(-)-Thujopsene (>85%)

Popular Products