EGFR-IN-85

• Target:

  EGFR

• Related Pathways:

  JAK/STAT signaling|||Angiogenesis|||Tyrosine Kinase/Adaptors

• Bioactivity:

  EGFR-IN-85 (Compound 1), an EGFR inhibitor, exhibits potent activity with an IC50 of 0.19 ?M against EGFRv? phosphorylation and can suppress intratumoral EGFR signaling. It is utilized in Glioblastoma (GBM) research [1].

• Smiles:

  N(C=1N=C(N2C=3C(C=C2)=CC=CN3)C=CN1)C4=C(OC)C=C(N(CCN(C)C)C)C(NC(C=C)=O)=C4

• Molecular Formula:

  C26H30N8O2

• Molecular Weight:

  486.57

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  1956378-29-2