YM-26734

• Description:

  YM-26734 is a competitive inhibitor of secretory phospholipase A2 (PLA2) that exhibits a broad inhibitory profile to several PLA2s[1].

• UNSPSC:

  12352005

• Target:

  Phospholipase

• Type:

  Reference compound

• Related Pathways:

  Metabolic Enzyme/Protease

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/ym-26734.html

• Purity:

  99.7

• Solubility:

  10 mM in DMSO

• Smiles:

  OC1=C(C(CCCCCCCCCCC)=O)C(O)=C(C(CCCCCCCCCCC)=O)C(O)=C1C2CC(C3=CC=C(O)C=C3)OC4=CC(O)=CC=C24

• Molecular Formula:

  C45H62O8

• Molecular Weight:

  730.97

• References & Citations:

  [1]Miyake A, et al. Suppression of inflammatory responses to 12-O-tetradecanoyl-phorbol-13-acetate and carrageenin by YM-26734, a selective inhibitor of extracellular group II phospholipase A2. Br J Pharmacol. 1993 Sep;110 (1) :447-53.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• Isoform:

  Phospholipase A

• CAS Number:

  [144337-18-8]