Products for Research Use Only
RegisterLogin

SNS-314

CAT: 0804-HY-108344Size: 1 EachDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-108344Size:1 Each
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
SNS-314 is a potent and selective aurora kinase inhibitor with IC50s of 9, 31, and 6 nM for aurora A, B and C, respectively[1].
CAS Number
1057249-41-8
UNSPSC
12352005
Target
Aurora Kinase
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Epigenetics
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/sns-314-1.html
Solubility
10 mM in DMSO
Smiles
O=C(NC1=NC=C(CCNC2=C3C(C=CS3)=NC=N2)S1)NC4=CC=CC(Cl)=C4
Molecular Formula
C18H15ClN6OS2
Molecular Weight
430.93
References & Citations
[1]Oslob JD, et al. Discovery of a potent and selective aurora kinase inhibitor. Bioorg Med Chem Lett. 2008 Sep 1;18 (17) :4880-4.|[2]Arbitrario JP, et al. SNS-314, a pan-Aurora kinase inhibitor, shows potent anti-tumor activity and dosing flexibility in vivo. Cancer Chemother Pharmacol. 2010 Mar;65 (4) :707-17.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 1
Isoform
Aurora A; Aurora B; Aurora C

Related Products

CatalogName
HY-10008-01SNS-032
HY-18626NK 314
HY-101350AQX-314
HY-10008R-01SNS-032 (Standard)
HY-123937-01THAL-SNS-032
HY-P991426MB-314
HY-W027857-01Coumarin 314
HY-W953102CRBN ligand-314
HY-108505-01QX-314 (chloride)
HY-101350-01QX-314 (bromide)

Alternative Products

CatalogName
BA3718-5.1SNS-314

Popular Products