Products for Research Use Only

UB-165

CAT: 0804-HY-107688Size: InquireDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-107688Size:Inquire
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
CAS Number
200432-86-6
UNSPSC Description
UB-165 is a nAChR agonist, being a full agonist of the α3β2 isoform and a partial agonist of the α4β2* isoform, with a Ki value of 0.27 nM for [3H]-nicotine binding in rat brain[1].
Target Antigen
nAChR
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel;Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/ub-165.html
Solubility
10 mM in DMSO
Smiles
ClC1=NC=C(C2=CCC[C@@]3([H])N[C@]2([H])CC3)C=C1
Molecular Weight
234.72
References & Citations
[1]Sharples CG, et al. UB-165: a novel nicotinic agonist with subtype selectivity implicates the alpha4beta2* subtype in the modulation of dopamine release from rat striatal synaptosomes. J Neurosci. 2000 Apr 15;20(8):2783-91.
Shipping Conditions
Room temperature
Clinical Information
No Development Reported