UB-165

• UNSPSC Description :

  UB-165 is a nAChR agonist, being a full agonist of the α3β2 isoform and a partial agonist of the α4β2* isoform, with a Ki value of 0.27 nM for [3H]-nicotine binding in rat brain[1].

• Target Antigen :

  nAChR

• Type :

  Reference compound

• Related Pathways :

  Membrane Transporter/Ion Channel;Neuronal Signaling

• Applications :

  Neuroscience-Neuromodulation

• Field of Research :

  Neurological Disease

• Assay Protocol :

  https://www.medchemexpress.com/ub-165.html

• Solubility :

  10 mM in DMSO

• Smiles :

  ClC1=NC=C(C2=CCC[C@@]3([H])N[C@]2([H])CC3)C=C1

• Molecular Weight :

  234.72

• References & Citations :

  [1]Sharples CG, et al. UB-165: a novel nicotinic agonist with subtype selectivity implicates the alpha4beta2* subtype in the modulation of dopamine release from rat striatal synaptosomes. J Neurosci. 2000 Apr 15;20(8):2783-91.

• Shipping Conditions :

  Room temperature

• Clinical Information :

  No Development Reported

• CAS Number :

  [200432-86-6]