UB-MBX-46

CAT: 0804-HY-179373Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-179373Size:1 Each
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
UB-MBX-46 is a potent and selective P2X7 receptor antagonist with IC50s of 0.514 nM (hP2X7R), 40.6 nM (rP2X7R), and 4.52 nM (mP2X7R), respectively. UB-MBX-46 interacts with the classical allosteric pocket of the human P2X7 receptor. UB-MBX-46 can be used for cancer, atherosclerosis, and neurode generation research[1].
UNSPSC
12352005
Target
P2X Receptor
Related Pathways
Membrane Transporter/Ion Channel
Field of Research
Cancer; Neurological Disease; Cardiovascular Disease
Smiles
O=C(NNC1=C(C=CC=C1)Cl)C23C(CC4(C)C5(C)C3)CC4(C)C5(C)C2
Molecular Formula
C21H27ClN2O
Molecular Weight
358.90
References & Citations
[1]Oken AC, et al. A polycyclic scaffold identified by structure-based drug design effectively inhibits the human P2X7 receptor. Nat Commun. 2025 Sep 15;16 (1) :8283.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
P2X7 Receptor

Related Products

CatalogName
HY-15291-01MBX-2982
HY-126742MBX-1162
HY-129318MBX-1066
HY-112565-01MBX-4132
HY-138997MBX-102 acid
HY-15291R-01MBX-2982 (Standard)
HY-P991420UB-925
HY-P991592UB-221
HY-107688UB-165
HY-107688AUB-165 (fumarate)

Alternative Products

CatalogName
M24040-01MBX-4132
bs-6524C-01MBX-2982
454218MBX 102
MBS5750705MBX 8025
B1997-25MBX-8025
MF-0148274-01MBX-1066
MBS132224-01MBX 2982
MF-0142575-01MBX-1162

Popular Products