TCH-165

• Description :

  TCH-165 is a small molecule modulator of proteasome assembly, which increases 20S levels and facilitates 20S-mediated protein degradation[1].

• UNSPSC :

  12352005

• Hazard Statement :

  H315, H319

• Target :

  Proteasome

• Type :

  Reference compound

• Related Pathways :

  Metabolic Enzyme/Protease

• Applications :

  Cancer-Kinase/protease

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/tch-165.html

• Purity :

  98.42

• Solubility :

  DMSO : 250 mg/mL (ultrasonic)

• Smiles :

  O=C([C@]1(C2=CC=CC=C2)N=C(C3=CC=C(OC)C=C3)N(CC4=CC=CC=C4)[C@@H]1C5=CC=C(NCC6=CC=CC=C6)C=C5)OCC

• Molecular Formula :

  C39H37N3O3

• Molecular Weight :

  595.73

• Precautions :

  H315, H319

• References & Citations :

  [1]Njomen E, et al. Small Molecule Modulation of Proteasome Assembly. Biochemistry. 2018 Jul 17;57 (28) :4214-4224.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [1446350-60-2]