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GT-1

CAT: 0804-HY-139698Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-139698Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
GT-1 (LCB10-0200), a siderophore-linked cephalosporin, is effective against clinical isolates of P. aeruginosa, Klebsiella oxytoca, Proteus spp., Serratia marcescens, and Enterobacter aerogenes.
CAS Number
[1401527-90-9]
Product Name Alternative
LCB10-0200
UNSPSC
12352005
Target
Antibiotic; Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/gt-1.html
Solubility
10 mM in DMSO
Smiles
OC1=CN(O)C(C(NCCNC2=C[N+](CC3=C(C([O-])=O)N4[C@@H]([C@H](NC(/C(C5=C(Cl)SC(N)=N5)=N\OC(C)(C)C(O)=O)=O)C4=O)SC3)=CN=C2N)=O)=CC1=O
Molecular Formula
C29H30ClN11O11S2
Molecular Weight
808.20
References & Citations
[1]Halasohoris SA, et al. In vitro and in vivo activity of GT-1, a novel siderophore cephalosporin, and GT-055, a broad-spectrum β-lactamase inhibitor, against biothreat and ESKAPE pathogens. J Antibiot (Tokyo) . 2021 Dec;74 (12) :884-892.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 4

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