GT-1

• Description:

  GT-1 (LCB10-0200), a siderophore-linked cephalosporin, is effective against clinical isolates of P. aeruginosa, Klebsiella oxytoca, Proteus spp., Serratia marcescens, and Enterobacter aerogenes.

• Product Name Alternative:

  LCB10-0200

• UNSPSC:

  12352005

• Target:

  Antibiotic; Bacterial

• Type:

  Reference compound

• Related Pathways:

  Anti-infection

• Field of Research:

  Infection

• Assay Protocol:

  https://www.medchemexpress.com/gt-1.html

• Solubility:

  10 mM in DMSO

• Smiles:

  OC1=CN(O)C(C(NCCNC2=C[N+](CC3=C(C([O-])=O)N4[C@@H]([C@H](NC(/C(C5=C(Cl)SC(N)=N5)=N\OC(C)(C)C(O)=O)=O)C4=O)SC3)=CN=C2N)=O)=CC1=O

• Molecular Formula:

  C29H30ClN11O11S2

• Molecular Weight:

  808.20

• References & Citations:

  [1]Halasohoris SA, et al. In vitro and in vivo activity of GT-1, a novel siderophore cephalosporin, and GT-055, a broad-spectrum β-lactamase inhibitor, against biothreat and ESKAPE pathogens. J Antibiot (Tokyo) . 2021 Dec;74 (12) :884-892.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  Phase 4

• CAS Number:

  [1401527-90-9]