MT-7716 (free base)

• Description:

  MT-7716 free base (W-212393) is a selective non-peptide nociceptin receptor (NOP) agonist and promising potential treatment drug for alcohol abuse and relapse prevention[1].

• Product Name Alternative:

  W-212393

• UNSPSC:

  12352005

• Target:

  Opioid Receptor

• Type:

  Reference compound

• Related Pathways:

  GPCR/G Protein; Neuronal Signaling

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/mt-7716-free-base.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(CN(C1=O)C2=CC=CC=C2N1C3CCN(CC3)[C@@H]4CC5=C6C4=CC=CC6=CC=C5)NC

• Molecular Formula:

  C27H28N4O2

• Molecular Weight:

  440.54

• References & Citations:

  [1]de Guglielmo G, et al, MT-7716, a potent NOP receptor agonist, preferentially reduces ethanol seeking and reinforcement in post-dependent rats. Addict Biol. 2015 Jul;20 (4) :643-51.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• Isoform:

  NOP Receptor/ORL1

• CAS Number:

  [610323-32-5]