CP-122288

• Description:

  CP-122288, a highly potent inhibitor of neurogenic inflammation, can be used in migraine study[1].

• UNSPSC:

  12352005

• Target:

  5-HT Receptor

• Type:

  Reference compound

• Related Pathways:

  GPCR/G Protein; Neuronal Signaling

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Inflammation/Immunology; Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/cp-122288.html

• Solubility:

  10 mM in DMSO

• Smiles:

  CNS (CC1=CC2=C (C=C1) NC=C2C[C@@H]3N (CCC3) C) (=O) =O

• Molecular Formula:

  C16H23N3O2S

• Molecular Weight:

  321.44

• References & Citations:

  [1]K I Roon, et al. No acute antimigraine efficacy of CP-122,288, a highly potent inhibitor of neurogenic inflammation: results of two randomized, double-blind, placebo-controlled clinical trials. Ann Neurol. 2000 Feb;47 (2) :238-41.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  Phase 2

• CAS Number:

  143321-74-8