BRD4-IN-9

• Description:

  BRD4-IN-9 is an orally active BRD4 inhibitor with an IC50 value of 9.4 nM. BRD4-IN-9 can suppress tumor growth in a mouse melanoma xenograft model[1].

• UNSPSC:

  12352005

• Target:

  Epigenetic Reader Domain

• Type:

  Reference compound

• Related Pathways:

  Epigenetics

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/brd4-in-9.html

• Smiles:

  CN(C(C=C1)=O)C=C1C2=CC=C(N=C(C3CCOCC3)N4)C4=C2OC5=CC=CC=C5

• Molecular Formula:

  C24H23N3O3

• Molecular Weight:

  401.46

• References & Citations:

  [1]Horai Y, et al. A novel 7-phenoxy-benzimidazole derivative as a potent and orally available BRD4 inhibitor for the treatment of melanoma. Bioorg Med Chem. 2024 Oct 1;112:117882.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [2468959-08-0]