BRD4-IN-9

• Description :

  BRD4-IN-9 is an orally active BRD4 inhibitor with an IC50 value of 9.4 nM. BRD4-IN-9 can suppress tumor growth in a mouse melanoma xenograft model[1].

• CAS Number :

  [2468959-08-0]

• UNSPSC :

  12352005

• Target :

  Epigenetic Reader Domain

• Type :

  Reference compound

• Related Pathways :

  Epigenetics

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/brd4-in-9.html

• Smiles :

  CN(C(C=C1)=O)C=C1C2=CC=C(N=C(C3CCOCC3)N4)C4=C2OC5=CC=CC=C5

• Molecular Formula :

  C24H23N3O3

• Molecular Weight :

  401.46

• References & Citations :

  [1]Horai Y, et al. A novel 7-phenoxy-benzimidazole derivative as a potent and orally available BRD4 inhibitor for the treatment of melanoma. Bioorg Med Chem. 2024 Oct 1;112:117882.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported