BRD4-IN-9

CAT: 0804-HY-162892Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-162892Size:1 Each
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
BRD4-IN-9 is an orally active BRD4 inhibitor with an IC50 value of 9.4 nM. BRD4-IN-9 can suppress tumor growth in a mouse melanoma xenograft model[1].
CAS Number
[2468959-08-0]
UNSPSC
12352005
Target
Epigenetic Reader Domain
Type
Reference compound
Related Pathways
Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/brd4-in-9.html
Smiles
CN(C(C=C1)=O)C=C1C2=CC=C(N=C(C3CCOCC3)N4)C4=C2OC5=CC=CC=C5
Molecular Formula
C24H23N3O3
Molecular Weight
401.46
References & Citations
[1]Horai Y, et al. A novel 7-phenoxy-benzimidazole derivative as a potent and orally available BRD4 inhibitor for the treatment of melanoma. Bioorg Med Chem. 2024 Oct 1;112:117882.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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