M62812 (free base)

M62812 (free base)

• CAS Number: 613262-61-6
• UNSPSC Description: M62812 (free base) is a toll-like receptor 4 (TLR4) signal transduction inhibitor. M62812 can suppress endothelial cell and leukocyte activation and prevents lethal septic shock in mice. M62812 can be used for the research of sepsis[1].
• Target Antigen: Toll-like Receptor (TLR)
• Type: Reference compound
• Related Pathways: Immunology/Inflammation
• Applications: COVID-19-immunoregulation
• Field of Research: Inflammation/Immunology
• Assay Protocol: https://www.medchemexpress.com/m62812-free-base.html
• Solubility: 10 mM in DMSO
• Smiles: NC1=NSC2=C1C=CC(OC3=CC=CC=C3N)=C2
• Molecular Weight: 257.31
• References & Citations: [1]Nakamura M, et al. Toll-like receptor 4 signal transduction inhibitor, M62812, suppresses endothelial cell and leukocyte activation and prevents lethal septic shock in mice. Eur J Pharmacol. 2007;569(3):237-243.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported