PF-945863

• UNSPSC Description:

  PF-945863 is an orally active macrolide antibiotic that can be used for the research of multidrug resistant respiratory tract bacterial strains[1][2].

• Target Antigen:

  Antibiotic

• Type:

  Reference compound

• Related Pathways:

  Anti-infection

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Infection

• Assay Protocol:

  https://www.medchemexpress.com/pf-945863.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C1N(C2CN([C@@H](C3=CC=NC4=C3C=CC=N4)C)C2)[C@@]([C@H]5C)([H])[C@@](C)([C@H](OC([C@@H](C([C@H](C)[C@@H](O[C@@]6([H])[C@@H]([C@H](C[C@@H](C)O6)N(C)C)O)[C@@](OC)(C)C[C@@H](C)C5=O)=O)C)=O)CC)O1

• Molecular Weight:

  824.01

• References & Citations:

  [1]Zientek M, et al. In vitro-in vivo correlation for intrinsic clearance for drugs metabolized by human aldehyde oxidase. Drug Metab Dispos. 2010;38(8):1322-1327.|[2]Magee TV, et al. Discovery of azetidinyl ketolides for the treatment of susceptible and multidrug resistant community-acquired respiratory tract infections. J Med Chem. 2009;52(23):7446-7457.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  893556-85-9