CP-135807

• Description :

  CP-135807 is an orally active and selective 5-HT1D agonist (IC50=3.1 nM), bovine) . CP-135807 mediates central psychoactivity and can be used in antidepressant research[1][2].

• UNSPSC :

  12352005

• Hazard Statement :

  H302, H315, H319, H335

• Target :

  5-HT Receptor

• Type :

  Reference compound

• Related Pathways :

  GPCR/G Protein; Neuronal Signaling

• Applications :

  Neuroscience-Neuromodulation

• Field of Research :

  Neurological Disease

• Assay Protocol :

  https://www.medchemexpress.com/cp-135807.html

• Solubility :

  10 mM in DMSO

• Smiles :

  O=[N+](C1=CC=CN=C1NC2=CC3=C(NC=C3C[C@@H]4N(C)CCC4)C=C2)[O-]

• Molecular Formula :

  C19H21N5O2

• Molecular Weight :

  351.40

• Precautions :

  H302, H315, H319, H335

• References & Citations :

  [1]Mansbach RS, et al. CP-135,807, a selective 5-HT1D agonist: effects in drug discrimination and punishment procedures in the pigeon. Psychopharmacology (Berl) . 1996 Dec;128 (3) :313-9. |[2]Macor J E, et al. Use of 2, 5-Dimethylpyrrole as an Amino-Protecting Group in an Efficient Synthesis of 5-Amino-3-[ (N-methyl-pyrrolidin-2 (R) -yl) methyl] indole[J]. The Journal of Organic Chemistry, 1994, 59 (24) : 7496-7498.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  4°C (Powder, protect from light)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• Isoform :

  5-HT1 Receptor; mLAG-3

• CAS Number :

  [151272-90-1]