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CP-135807

CAT: 0804-HY-103092Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-103092Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CP-135807 is an orally active and selective 5-HT1D agonist (IC50=3.1 nM), bovine) . CP-135807 mediates central psychoactivity and can be used in antidepressant research[1][2].
CAS Number
151272-90-1
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
5-HT Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/cp-135807.html
Solubility
10 mM in DMSO
Smiles
O=[N+](C1=CC=CN=C1NC2=CC3=C(NC=C3C[C@@H]4N(C)CCC4)C=C2)[O-]
Molecular Formula
C19H21N5O2
Molecular Weight
351.40
Precautions
H302, H315, H319, H335
References & Citations
[1]Mansbach RS, et al. CP-135,807, a selective 5-HT1D agonist: effects in drug discrimination and punishment procedures in the pigeon. Psychopharmacology (Berl) . 1996 Dec;128 (3) :313-9. |[2]Macor J E, et al. Use of 2, 5-Dimethylpyrrole as an Amino-Protecting Group in an Efficient Synthesis of 5-Amino-3-[ (N-methyl-pyrrolidin-2 (R) -yl) methyl] indole[J]. The Journal of Organic Chemistry, 1994, 59 (24) : 7496-7498.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
5-HT1 Receptor; mLAG-3

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