AT-112

• Description :

  AT-112 is a ketotanserin analogue. AT-112 has hemodynamic effects. AT-112 significantly reduces portal vein branch blood flow and portal vein pressure. AT-112 can be used to study the pathogenesis of portal hypertension[1].

• UNSPSC :

  12352005

• Target :

  Drug Derivative

• Type :

  Reference compound

• Related Pathways :

  Others

• Applications :

  Neuroscience-Neuromodulation

• Field of Research :

  Cardiovascular Disease

• Assay Protocol :

  https://www.medchemexpress.com/at-112.html

• Solubility :

  10 mM in DMSO

• Smiles :

  O=C1NC2=C(C=CC=C2)C3=NC(CN4CCN(C5=CC=CC=C5)CC4)CN13

• Molecular Formula :

  C21H23N5O

• Molecular Weight :

  361.44

• References & Citations :

  [1]Lin HC, et al The hemodynamic effects of AT-112, an analog of ketanserin, in portal hypertensive rats. Pharmacology. 1997 Jan;54 (1) :16-23.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [139047-55-5]