AChE-IN-17

CAT: 0804-HY-N10384Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-N10384Size:1 Each
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Description
AChE-IN-17 (compound 1) is a potent AChE inhibitor with an IC50 value of 28.98 μM. AChE-IN-17 can significantly prevent H2O2-induced PC12 cell death, exhibiting excellent neuroprotective effect. AChE-IN-17 can be used for researching neurodegenerative diseases (NDs) [1].
CAS Number
[460345-17-9]
UNSPSC
12352005
Target
Cholinesterase (ChE)
Type
Natural Products
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/ache-in-17.html
Solubility
10 mM in DMSO
Smiles
C=CC(C)(C1=CC([C@@H]2CC(C3=C(C=C(C(C/C=C(C)\C)=C3O2)O)O)=O)=C(C=C1O)O)C
Molecular Formula
C25H28O6
Molecular Weight
424.49
References & Citations
[1]Santi MD, et al. Neuroprotective effects of prenylated flavanones isolated from Dalea species, in vitro and in silico studies. Eur J Med Chem. 2020;206:112718.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
AChE

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