AChE-IN-17

• Description :

  AChE-IN-17 (compound 1) is a potent AChE inhibitor with an IC50 value of 28.98 μM. AChE-IN-17 can significantly prevent H2O2-induced PC12 cell death, exhibiting excellent neuroprotective effect. AChE-IN-17 can be used for researching neurodegenerative diseases (NDs) [1].

• UNSPSC :

  12352005

• Target :

  Cholinesterase (ChE)

• Type :

  Natural Products

• Related Pathways :

  Neuronal Signaling

• Applications :

  Neuroscience-Neurodegeneration

• Field of Research :

  Neurological Disease

• Assay Protocol :

  https://www.medchemexpress.com/ache-in-17.html

• Solubility :

  10 mM in DMSO

• Smiles :

  C=CC(C)(C1=CC([C@@H]2CC(C3=C(C=C(C(C/C=C(C)\C)=C3O2)O)O)=O)=C(C=C1O)O)C

• Molecular Formula :

  C25H28O6

• Molecular Weight :

  424.49

• References & Citations :

  [1]Santi MD, et al. Neuroprotective effects of prenylated flavanones isolated from Dalea species, in vitro and in silico studies. Eur J Med Chem. 2020;206:112718.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Natural Products

• Clinical Information :

  No Development Reported

• Isoform :

  AChE

• CAS Number :

  [460345-17-9]