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(-) - (S) -Cibenzoline-d4

CAT: 0804-HY-106577ASSize: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-106577ASSize:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
(-) - (S) -Cibenzoline-d4 (Escibenzoline-d4) is deuterium labeled (-) - (S) -Cibenzoline. (-) - (S) -Cibenzoline (Escibenzoline), a S (+) -enantiomer of Cibenzoline, is an antiarrhythmic agent[1][2].
Product Name Alternative
Escibenzoline-d4; (-) - (S) -Cifenline-d4; (-) - (S) -Ro 22-7796-d4
UNSPSC
12352005
Target
Isotope-Labeled Compounds; Potassium Channel
Type
Isotope-Labeled Compounds
Related Pathways
Membrane Transporter/Ion Channel; Others
Field of Research
Metabolic Disease
Smiles
[2H]C1([2H])C([2H])([2H])N=C([C@@H]2C(C3=CC=CC=C3)(C4=CC=CC=C4)C2)N1
Molecular Formula
C18H14D4N2
Molecular Weight
266.37
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53 (2) :211-216.|[2]T Niwa, et al. Stereoselective metabolism of cibenzoline, an antiarrhythmic drug, by human and rat liver microsomes: possible involvement of CYP2D and CYP3A. Drug Metab Dispos. 2000 Sep;28 (9) :1128-34.
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported