(-) - (S) -Cibenzoline

• Description :

  (-) - (S) -Cibenzoline (Escibenzoline), a S (+) -enantiomer of Cibenzoline, is an antiarrhythmic agent[1].

• Product Name Alternative :

  Escibenzoline; (-) - (S) -Cifenline; (-) - (S) -Ro 22-7796

• UNSPSC :

  12352005

• Target :

  Potassium Channel

• Type :

  Reference compound

• Related Pathways :

  Membrane Transporter/Ion Channel

• Applications :

  Metabolism-protein/nucleotide metabolism

• Field of Research :

  Metabolic Disease

• Assay Protocol :

  https://www.medchemexpress.com/minus-s-cibenzoline.html

• Solubility :

  10 mM in DMSO

• Smiles :

  [H][C@@]1(C2=NCCN2)C(C3=CC=CC=C3)(C4=CC=CC=C4)C1

• Molecular Formula :

  C18H18N2

• Molecular Weight :

  262.35

• References & Citations :

  [1]T Niwa, et al. Stereoselective metabolism of cibenzoline, an antiarrhythmic drug, by human and rat liver microsomes: possible involvement of CYP2D and CYP3A. Drug Metab Dispos. 2000 Sep;28 (9) :1128-34.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [103419-18-7]