HDAC-MB

• Description:

  HDAC-MB a probe that is activated by HDAC6 and can detect and eliminate glioma cells through activation by HDAC6. HDAC-MB reveals antimetastatic and antiproliferative properties, inhibits glioma invasion and induces cellular apoptosis[1].

• UNSPSC:

  12171500

• Target:

  Fluorescent Dye; Monoamine Oxidase

• Type:

  Dye Reagents

• Related Pathways:

  Neuronal Signaling; Others

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/hdac-mb.html

• Solubility:

  10 mM in DMSO

• Smiles:

  CC(NCCCCCC(OC1=CC=C(C=C1)COC(N2C3=CC=C(C=C3SC4=CC(N(C)C)=CC=C42)N(C)C)=O)=O)=O

• Molecular Formula:

  C32H38N4O5S

• Molecular Weight:

  590.73

• References & Citations:

  [1]Wei W, et al., HDAC6-Activatable Multifunctional Near-Infrared Probe for Glioma Cell Detection and Elimination. Anal Chem. 2024 Feb 13;96 (6) :2406-2414.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Dye Reagents

• Clinical Information:

  No Development Reported