CDK2/4/6-IN-1

CDK2/4/6-IN-1

• CAS Number: 2803837-13-8
• UNSPSC Description: CDK2/4/6-IN-1(example 29) is a CDK2/4/6 inhibitor with IC50 values of 2.5, 23.7 and 44.3 nM for CDK2, CDK4 and CDK6, respectively. CDK2/4/6-IN-1 can be used in cancer research[1]. CDK2/4/6-IN-1 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
• Target Antigen: CDK
• Type: Reference compound
• Related Pathways: Cell Cycle/DNA Damage
• Applications: Cancer-Kinase/protease
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/cdk2-4-6-in-1.html
• Solubility: 10 mM in DMSO
• Smiles: O=S(C1=CC=C(NC2=NC=C3C(N([C@@H]4CCC[C@]4(O)C)C(C(C#C)=C3)=O)=N2)C=C1)(C)=O
• Molecular Weight: 438.50
• References & Citations: [1]ZHANG YAN, et al. Cdk2/4/6 inhibitor, preparation method therefor, and application thereof. WO2022152259 A1.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported