Products for Research Use Only
RegisterLogin

AChE/BuChE-IN-5

CAT: 0804-HY-163537Size: 1 EachDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-163537Size:1 Each
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
AChE/BuChE-IN-5 (compound 5a) is a dual target inhibitor. AChE/BuChE-IN-5 has excellent nanomolar inhibitory activity on acetylcholinesterase (AChE) (IC50=46.9 nM) and butyryl cholinesterase (BuChE) (IC50=3.5 nM) . AChE/BuChE-IN-5 can be used for Alzheimer's Disease research[1].
UNSPSC
12352005
Target
Cholinesterase (ChE)
Type
Reference compound
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/ache-buche-in-5.html
Solubility
10 mM in DMSO
Smiles
C1(NC2=NN=C(O2)C3=CC(C4=CC=CC=C4)=CN=C3)=CC=CC=C1
Molecular Formula
C19H14N4O
Molecular Weight
314.34
References & Citations
[1]Zaafar D, et al. Unleashing new MTDL AChE and BuChE inhibitors as potential anti-AD therapeutic agents: In vitro, in vivo and in silico studies[J]. International Journal of Biological Macromolecules, 2024: 131740.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
AChE; BChE

Related Products

CatalogName
HY-178141AChE/BuChE-IN-7
HY-146142AChE/BuChE-IN-2
HY-144392AChE/BuChE-IN-1
HY-147939AChE/BuChE-IN-3
HY-170561AChE/BuChE-IN-6
HY-155349-01AChE/BuChE-IN-4
HY-149090AChE/BuChE/MAO-B-IN-2
HY-151562AChE/BuChE/MAO-B-IN-1
HY-150585BuChE-IN-5
HY-144272AChE-IN-5

Alternative Products

CatalogName
T209615-01AChE/BuChE-IN-5
MBS5806798AChE/BuChE-IN-3
MBS5803556AChE/BuChE-IN-2
BUP09579-01AChE/BuChE-IN-4
T204119-01AChE/BuChE-IN-6
MBS5815053AChE/BuChE-IN-1
GTR19273979-01AChE/BuChE-IN-7
GTR19231010-01AChE/BuChE/MAO-B-IN-2
T61579-01BuChE-IN-5
GTR19184544-01AChE-IN-5

Popular Products