(E/Z) -HA155

CAT: 0804-HY-116100-01Size: 1 mgDry Ice: NoHazardous: No
CAT#:0804-HY-116100-01Size:1 mg
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Description
(E/Z) -HA155 is a potent autotaxin (ATX) type I inhibitor. (E/Z) -HA155 can be used for researching cancer, fibrotic diseases, inflammation, pain and angiogenesis[1].
CAS Number
[1229652-22-5]
Product Name Alternative
KPT-8602
UNSPSC
12352005
Hazard Statement
H302-H315-H319
Target
Phosphodiesterase (PDE)
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Inflammation/Immunology; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/e-z-ha155.html
Concentration
10mM
Purity
99.58
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
OB(O)C1=CC=C(C=C1)COC2=CC=C(C=C2)/C=C(C3=O)\SC(N3CC4=CC=C(C=C4)F)=O
Molecular Formula
C24H19BFNO5S
Molecular Weight
463.29
Precautions
P264-P270-P280-P302+P352-P305+P351+P338-P330-P362+P364-P501
References & Citations
[1]Joncour A, et al. Discovery, Structure-Activity Relationship, and Binding Mode of an Imidazo[1,2-a]pyridine Series of Autotaxin Inhibitors [published correction appears in J Med Chem. 2018 May 10;61 (9) :4270]. J Med Chem. 2017;60 (17) :7371-7392.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Autotaxin

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