WF-210

• Description :

  WF-210 is a potent procaspase-3 activator with an EC50 value of 0.95 μM. WF-210 induces Apoptosis. WF-210 has anti-tumor activity[1].

• UNSPSC :

  12352005

• Target :

  Apoptosis; Caspase

• Type :

  Reference compound

• Related Pathways :

  Apoptosis

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/wf-210.html

• Smiles :

  O=C(CN1CCN(CC1)CC2=NC(C3=CC=C(COC4=CC=C(C=C4)F)C=C3)=NO2)N/N=C/C5=CC=C(C=C5O)OCC6=CSC(CC7=CC=C8OCOC8=C7)=N6

• Molecular Formula :

  C41H38FN7O7S

• Molecular Weight :

  791.85

• References & Citations :

  [1]Wang F, et al. A novel small-molecule activator of procaspase-3 induces apoptosis in cancer cells and reduces tumor growth in human breast, liver and gallbladder cancer xenografts. Mol Oncol. 2014 Dec;8 (8) :1640-52.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• Isoform :

  Caspase 3

• CAS Number :

  [1242279-00-0]