WF-10129

• Description:

  WF-10129 is a cytotoxic steroidal compound isolated from the plant Physalis. WF-10129 inhibits liver cancer cell proliferation, induces apoptosis, interferes with metabolism, and significantly reduces lactate production in vitro and in vivo. WF-10129 can also exert anti-tumor activity by regulating the expression of related genes and proteins through the AKT-p53 pathway.

• UNSPSC:

  12352005

• Target:

  Akt; Apoptosis

• Type:

  Natural Products

• Related Pathways:

  Apoptosis; PI3K/Akt/mTOR

• Applications:

  Cancer-Kinase/protease

• Field of Research:

  Others

• Assay Protocol:

  https://www.medchemexpress.com/wf-10129.html

• Smiles:

  OC1=CC=C(C=C1)C[C@@H](C(O)=O)NC([C@H](C)N[C@H](C(O)=O)CC(CC[C@@H](O)C)=O)=O

• Molecular Formula:

  C20H28N2O8

• Molecular Weight:

  424.44

• References & Citations:

  [1]WF-10129, a novel angiotensin converting enzyme inhibitor produced by a fungus, Doratomyces putredinis

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Natural Products

• Clinical Information:

  No Development Reported

• CAS Number:

  [109075-64-1]