WF-10129

• Description :

  WF-10129 is a cytotoxic steroidal compound isolated from the plant Physalis. WF-10129 inhibits liver cancer cell proliferation, induces apoptosis, interferes with metabolism, and significantly reduces lactate production in vitro and in vivo. WF-10129 can also exert anti-tumor activity by regulating the expression of related genes and proteins through the AKT-p53 pathway.

• UNSPSC :

  12352005

• Target :

  Akt; Apoptosis

• Type :

  Natural Products

• Related Pathways :

  Apoptosis; PI3K/Akt/mTOR

• Applications :

  Cancer-Kinase/protease

• Field of Research :

  Others

• Assay Protocol :

  https://www.medchemexpress.com/wf-10129.html

• Smiles :

  OC1=CC=C(C=C1)C[C@@H](C(O)=O)NC([C@H](C)N[C@H](C(O)=O)CC(CC[C@@H](O)C)=O)=O

• Molecular Formula :

  C20H28N2O8

• Molecular Weight :

  424.44

• References & Citations :

  [1]WF-10129, a novel angiotensin converting enzyme inhibitor produced by a fungus, Doratomyces putredinis

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Natural Products

• Clinical Information :

  No Development Reported

• CAS Number :

  [109075-64-1]