WF-536

• Description :

  WF-536 is an orally active inhibitor of Rho-associated coiled-coil-containing protein kinase (ROCK) . WF-536 has tumor anti-metastatic activity. WF-536 can be used for the research of cancer[1].

• UNSPSC :

  12352005

• Target :

  ROCK

• Type :

  Reference compound

• Related Pathways :

  Cell Cycle/DNA Damage; Cytoskeleton; Stem Cell/Wnt; TGF-beta/Smad

• Applications :

  Cancer-Kinase/protease

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/wf-536.html

• Solubility :

  10 mM in DMSO

• Smiles :

  O=C(C1=CC=C(C=C1)[C@@H](C)N)NC2=CC=NC=C2.Cl

• Molecular Formula :

  C14H16ClN3O

• Molecular Weight :

  277.75

• References & Citations :

  [1]Nakajima, Masahide et al. Wf-536 prevents tumor metastasis by inhibiting both tumor motility and angiogenic actions. European journal of pharmacology vol. 459,2-3 (2003) : 113-20.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [539857-64-2]