WF-536

• UNSPSC Description:

  WF-536 is an orally active inhibitor of Rho-associated coiled-coil-containing protein kinase (ROCK). WF-536 has tumor anti-metastatic activity. WF-536 can be used for the research of cancer[1].

• Target Antigen:

  ROCK

• Type:

  Reference compound

• Related Pathways:

  Cell Cycle/DNA Damage;Cytoskeleton;Stem Cell/Wnt;TGF-beta/Smad

• Applications:

  Cancer-Kinase/protease

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/wf-536.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(C1=CC=C(C=C1)[C@@H](C)N)NC2=CC=NC=C2.Cl

• Molecular Weight:

  277.75

• References & Citations:

  [1]Nakajima, Masahide et al. Wf-536 prevents tumor metastasis by inhibiting both tumor motility and angiogenic actions. European journal of pharmacology vol. 459,2-3 (2003): 113-20.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  539857-64-2