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WF-536

CAT: 0804-HY-118837Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-118837Size:1 Each
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Description
WF-536 is an orally active inhibitor of Rho-associated coiled-coil-containing protein kinase (ROCK) . WF-536 has tumor anti-metastatic activity. WF-536 can be used for the research of cancer[1].
CAS Number
539857-64-2
UNSPSC
12352005
Target
ROCK
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Cytoskeleton; Stem Cell/Wnt; TGF-beta/Smad
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/wf-536.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=CC=C(C=C1)[C@@H](C)N)NC2=CC=NC=C2.Cl
Molecular Formula
C14H16ClN3O
Molecular Weight
277.75
References & Citations
[1]Nakajima, Masahide et al. Wf-536 prevents tumor metastasis by inhibiting both tumor motility and angiogenic actions. European journal of pharmacology vol. 459,2-3 (2003) : 113-20.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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