CCG-4986

CAT: 0804-HY-122251Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-122251Size:1 Each
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Description
CCG-4986 is an RGS protein inhibitor. CCG-4986 inhibits protein activity by covalently modifying the Cys-132 site of RGS4. CCG-4986 can be used to study diseases related to dysregulated G protein-coupled receptor (GPCR) signaling, such as Parkinson's disease and opioid addiction[1].
CAS Number
[7134-19-2]
UNSPSC
12352005
Hazard Statement
H319
Target
RGS Protein
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease; Others
Assay Protocol
https://www.medchemexpress.com/ccg-4986.html
Smiles
O=[N+](C1=CC=C(/S(OC)=N\S(=O)(C2=CC=C(Cl)C=C2)=O)C=C1)[O-]
Molecular Formula
C13H11ClN2O5S2
Molecular Weight
374.82
Precautions
P264-P280-P305+P351+P338
References & Citations
[1]Kimple AJ, et al. The RGS protein inhibitor CCG-4986 is a covalent modifier of the RGS4 Galpha-interaction face. Biochim Biophys Acta. 2007 Sep;1774 (9) :1213-20.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
RGS4

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