Products for Research Use Only
RegisterLogin

CCG-232601

CAT: 0804-HY-111432Size: 1 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-111432Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
CCG-232601 (compound 8f) is a potent and orally active Rho/MRTF/SRF transcriptional pathway inhibitor. CCG-232601 inhibits the development of Bleomycin-induced dermal fibrosis in mice. CCG-232601 has the potential for the research of antifibrotic for systemic scleroderma[1].
CAS Number
1922099-21-5
UNSPSC
12352005
Target
Ras
Type
Reference compound
Related Pathways
GPCR/G Protein; MAPK/ERK Pathway
Applications
Neuroscience-Neuromodulation
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/ccg-232601.html
Purity
99.00
Solubility
DMSO : 40 mg/mL (ultrasonic; warming)
Smiles
O=C(C1CN(C(C2=CC=CC(C3=CC=NC=C3)=C2)=O)CC(F)(F)C1)NC4=CC=C(Cl)C=C4
Molecular Formula
C24H20ClF2N3O2
Molecular Weight
455.88
References & Citations
[1]Hutchings KM, et al. Pharmacokinetic optimitzation of CCG-203971: Novel inhibitors of the Rho/MRTF/SRF transcriptional pathway as potential antifibrotic therapeutics for systemic scleroderma. Bioorg Med Chem Lett. 2017 Apr 15;27 (8) :1744-1749.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Related Products

CatalogName
HY-150040CCG-273463
HY-130011CCG-232964
HY-122251CCG-4986
HY-U00431-01CCG 203769
HY-13991-01CCG-1423
HY-70074-01CCG-63802
HY-110054CCG-2046
HY-108361-01CCG-203971
HY-120855-01CCG-100602
HY-70075-01CCG-63808

Alternative Products

CatalogName
GTR19197941-01CCG-232601
A24545-10CCG-232601 10mg
A24545-50CCG-232601 50mg
A24545-1CCG-232601 1mg
A24545-5CCG-232601 5mg
M23376-01CCG-100602
B4921-10CCG 203971
B4897-5.1CCG-1423
T62986-01CCG-271423
474080CCG-203971

Popular Products