CCG-100602

CAT: 0804-HY-120855-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0804-HY-120855-01Size:5 mg
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
CCG-100602 is a specific inhibitor of myocardin-related transcription factor A/serum response factor (MRTF-A/SRF) signaling. CCG-100602 specifically block MRTF-A nuclear localization and thus inhibit the fibrogenic transcription factor SRF[1][2].
CAS Number
[1207113-88-9]
UNSPSC
12352005
Hazard Statement
H302, H315, H319
Target
Ras
Type
Reference compound
Related Pathways
GPCR/G Protein; MAPK/ERK Pathway
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/ccg-100602.html
Purity
99.29
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
ClC1=CC=C(NC(C2CN(C(C3=CC(C(F)(F)F)=CC(C(F)(F)F)=C3)=O)CCC2)=O)C=C1
Molecular Formula
C21H17ClF6N2O2
Molecular Weight
478.82
Precautions
H302, H315, H319
References & Citations
[1]Yoon Jeong Choi, et al. Umbilical cord/placenta-derived mesenchymal stem cells inhibit fibrogenic activation in human intestinal myofibroblasts via inhibition of myocardin-related transcription factor A. Stem Cell Res Ther. 2019 Sep 23;10 (1) :291.|[2]Laura Hyväri, et al. Myocardin-Related Transcription Factor A (MRTF-A) Regulates the Balance between Adipogenesis and Osteogenesis of Human Adipose Stem Cells. Stem Cells Int. 2020 Sep 22;2020:8853541.|[3]Ning Zhou, et al. Rho Kinase Regulates Aortic Vascular Smooth Muscle Cell Stiffness Via Actin/SRF/Myocardin in Hypertension. Cell Physiol Biochem. 2017;44 (2) :701-715.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Related Products

CatalogName
HY-150040CCG-273463
HY-U00431-01CCG 203769
HY-13991-01CCG-1423
HY-130011CCG-232964
HY-122251CCG-4986
HY-111432CCG-232601
HY-108361-01CCG-203971
HY-70074-01CCG-63802
HY-110054CCG-2046
HY-150039CCG-271423

Alternative Products

CatalogName
M23376-01CCG-100602
A24567-5CCG-100602 5mg
A24567-100CCG-100602 100mg
A24567-10CCG-100602 10mg
A24567-50CCG-100602 50mg
MBS3602895-01CCG-224406
MBS386736-01CCG-63802
MBS386737-01CCG-63808
MBS3841904-01CCG-203971
C17134-01CCG 50014

Popular Products