CCG-271423

• Target:

  GRK|||Others

• Related Pathways:

  Others|||GPCR/G Protein

• Bioactivity:

  CCG-271423 is a potent and selective inhibitor of GRK5, demonstrating activity against GRK5 (IC50: 0.0021 ?M) and GRK2 (IC50: 44 ?M) ; it reduces Ca2+ transients and inhibits cardiomyocyte contractility.

• Smiles:

  C (=C\1/C=2C (NC1=O) =CC=C (C (N[C@H] (C) C3=CC=CC=C3) =O) C2) \C4=C (C) C (C (NCC#C) =O) =C (C) N4

• Molecular Formula:

  C28H26N4O3

• Molecular Weight:

  466.53

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2750413-88-6