CCG-271423

• Target :

  GRK|||Others

• Related Pathways :

  Others|||GPCR/G Protein

• Bioactivity :

  CCG-271423 is a potent and selective inhibitor of GRK5, demonstrating activity against GRK5 (IC50: 0.0021 ?M) and GRK2 (IC50: 44 ?M) ; it reduces Ca2+ transients and inhibits cardiomyocyte contractility.

• Smiles :

  C(=C\1/C=2C(NC1=O)=CC=C(C(N[C@H](C)C3=CC=CC=C3)=O)C2)\C4=C(C)C(C(NCC#C)=O)=C(C)N4

• Molecular Formula :

  C28H26N4O3

• Molecular Weight :

  466.53

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  2750413-88-6