CCG-203971

• Target:

  Rho|||Ras

• Related Pathways:

  Cell Cycle/Checkpoint|||MAPK|||GPCR/G Protein

• Purity:

  0.995

• Bioactivity:

  CCG-203971 is an inhibitor of SRE activation in the prostate cancer cell line PC-3 (IC50: 6.4 ?M), with 87% inhibition of SRE activation achieved at 100 ?M. This compound also inhibits PC-3 cell migration (IC50: 4.2 ?M), as determined by a scratch wound assay. CCG-203971 (CCG203971) causes no cytotoxicity when evaluated by the WST-1 assay. It is well tolerated in normal mice up to doses of 100 mg/kg given intraperitoneally over five days.

• Smiles:

  Clc1ccc(NC(=O)C2CCCN(C2)C(=O)c2cccc(c2)-c2ccco2)cc1

• Molecular Formula:

  C23H21ClN2O3

• Molecular Weight:

  408.88

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  1443437-74-8