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CCG-203971

CAT: 0931-T4306-01Size: 1 mL - 10 mM (in DMSO)Dry Ice: NoHazardous: No
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CAT#:0931-T4306-01Size:1 mL - 10 mM (in DMSO)
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1443437-74-8
Target
Rho, Ras
Related Pathways
Cell Cycle/Checkpoint, MAPK, GPCR/G Protein
Purity
0.995
Bioactivity
CCG-203971 is an inhibitor of SRE activation in the prostate cancer cell line PC-3 (IC50: 6.4 μM), with 87% inhibition of SRE activation achieved at 100 μM. This compound also inhibits PC-3 cell migration (IC50: 4.2 μM), as determined by a scratch wound assay. CCG-203971 (CCG203971) causes no cytotoxicity when evaluated by the WST-1 assay. It is well tolerated in normal mice up to doses of 100 mg/kg given intraperitoneally over five days.
Smiles
Clc1ccc(NC(=O)C2CCCN(C2)C(=O)c2cccc(c2)-c2ccco2)cc1
Molecular Formula
C23H21ClN2O3
Molecular Weight
408.88
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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B4921-50CCG 203971
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