Z-IETD-AFC

Z-IETD-AFC

• CAS Number: 219138-02-0
• UNSPSC Description: Z-IETD-AFC, a specific fluorescence substrate, can be used to determine the caspase-8 catalytic activity[1].
• Target Antigen: Fluorescent Dye
• Type: Dye Reagents
• Related Pathways: Others
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/z-ietd-afc.html
• Purity: 99.78
• Solubility: H2O : 5 mg/mL (ultrasonic)
• Smiles: O=C1OC2=C(C(C(F)(F)F)=C1)C=CC(NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(OCC3=CC=CC=C3)=O)[C@H](CC)C)=O)CCC(O)=O)=O)[C@@H](C)O)=O)CC(O)=O)=O)=C2
• Molecular Weight: 821.75
• References & Citations: [1]Boudard D, et al. Increased caspase-3 activity in refractory anemias: lack of evidence for Fas pathway implication. Leukemia. 2002;16(11):2343-2345.
• Shipping Conditions: Blue Ice
• Storage Conditions: -80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture and light, under nitrogen)
• Clinical Information: No Development Reported