Z-IETD-pNA

Z-IETD-pNA

• CAS Number: 348079-18-5
• UNSPSC Description: Z-IETD-pNA (Z-Ile-Glu-Thr-Asp-pNA) is a colorimetric caspase-8 and granzyme B substrate. Z-IETD-pNA is hydrlyzed by caspase 8 to generate pNA[1].
• Target Antigen: Caspase
• Type: Peptides
• Related Pathways: Apoptosis
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/z-ietd-pna.html
• Solubility: 10 mM in DMSO
• Smiles: O=C(OCC1=CC=CC=C1)N[C@@H]([C@@H](C)CC)C(N[C@@H](CCC(O)=O)C(N[C@@H]([C@H](O)C)C(N[C@@H](CC(O)=O)C(NC2=CC=C(C=C2)[N+]([O-])=O)=O)=O)=O)=O
• Molecular Weight: 730.72
• References & Citations: [1]Yu-Hsuan Lan, et al. Death receptor 5-mediated TNFR family signaling pathways modulate γ-humulene-induced apoptosis in human colorectal cancer HT29 cells. Oncol Rep. 2011 Feb;25(2):419-24.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported