Ac-IETD-AFC
CAT:
804-HY-P1169-03
Size:
10 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No

Ac-IETD-AFC
- CAS Number: 211990-57-7
- UNSPSC Description: Ac-IETD-AFC is a fluorogenic substrate of caspase-8, caspase-3, caspase-10, and granzyme B[1].
- Target Antigen: Caspase
- Type: Dye Reagents
- Related Pathways: Apoptosis
- Field of Research: Others
- Assay Protocol: https://www.medchemexpress.com/ac-ietd-afc.html
- Purity: 99.91
- Solubility: DMSO : 125 mg/mL (ultrasonic)|H2O : < 0.1 mg/mL (ultrasonic)
- Smiles: FC(F)(C(C(C(O1)=C2)=CC=C2NC([C@H](CC(O)=O)NC([C@H]([C@H](O)C)NC([C@H](CCC(O)=O)NC([C@@H](NC(C)=O)[C@@H](C)CC)=O)=O)=O)=O)=CC1=O)F
- Molecular Weight: 729.65
- References & Citations: [1][1]Kazimierz Weglarczyk, et al. Caspase-8 activation precedes alterations of mitochondrial membrane potential during monocyte apoptosis induced by phagocytosis and killing of Staphylococcus aureus. Infect Immun. 2004 May;72(5):2590-7. |[2]Przemysław Reszka, et al. Synthesis, enzymatic evaluation, and docking studies of fluorogenic caspase 8 tetrapeptide substrates. ChemMedChem. 2010 Jan;5(1):103-17.
- Shipping Conditions: Blue Ice
- Storage Conditions: -80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture and light)
- Clinical Information: No Development Reported