Dronedarone (Standard)

CAT: 0804-HY-A0016R-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0804-HY-A0016R-01Size:5 mg
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Description
Dronedarone (Standard) is the analytical standard of Dronedarone. This product is intended for research and analytical applications. Dronedarone (SR 33589), a derivative of amiodarone (HY-14187), is a class III antiarrhythmic agent for the study of atrial fibrillation (AF) and atrial flutter. Dronedarone is a potent blocker of multiple ion currents, including potassium current, sodium current, and L-type calcium current, and exhibits antiadrenergic effects by noncompetitive binding to β-adrenergic receptors. Dronedarone is a substrate for and a moderate inhibitor of CYP3A4[1].
CAS Number
[141626-36-0]
Product Name Alternative
SR 33589 (Standard)
UNSPSC
12352005
Target
Adrenergic Receptor; Autophagy; Calcium Channel; Cytochrome P450; mAChR; Reference Standards; Sodium Channel
Type
Reference Standards
Related Pathways
Autophagy; GPCR/G Protein; Membrane Transporter/Ion Channel; Metabolic Enzyme/Protease; Neuronal Signaling; Others
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/dronedarone-standard.html
Smiles
CCCCC1=C(C2=C(C=CC(NS(C)(=O)=O)=C2)O1)C(C3=CC=C(C=C3)OCCCN(CCCC)CCCC)=O
Molecular Formula
C31H44N2O5S
Molecular Weight
556.76
References & Citations
[1]Chinmay Patel, et al. Dronedarone. Circulation. 2009 Aug 18;120 (7) :636-44.|[2]Katarzyna M Sawicka, et al. Influence of dronedarone (a class III antiarrhythmic drug) on the anticonvulsant potency of four classical antiepileptic drugs in the tonic-clonic seizure model in mice. J Neural Transm (Vienna) . 2019 Feb;126 (2) :115-122.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards

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