Products for Research Use Only
RegisterLogin

Dronedarone-d6

CAT: 0804-HY-A0016S3Size: 1 EachDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-A0016S3Size:1 Each
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Dronedarone-d6 (SR 33589-d6) is deuterium labeled Dronedarone. Dronedarone (SR 33589), a derivative of amiodarone , is a class III antiarrhythmic agent for the study of atrial fibrillation (AF) and atrial flutter. Dronedarone is a potent blocker of multiple ion currents, including potassium current, sodium current, and L-type calcium current, and exhibits antiadrenergic effects by noncompetitive binding to β-adrenergic receptors. Dronedarone is a substrate for and a moderate inhibitor of CYP3A4[1].
CAS Number
1132693-87-8
Product Name Alternative
SR 33589-d6
UNSPSC
12352211
Target
Adrenergic Receptor; Autophagy; Calcium Channel; Cytochrome P450; Isotope-Labeled Compounds; mAChR; Sodium Channel
Related Pathways
Autophagy; GPCR/G Protein; Membrane Transporter/Ion Channel; Metabolic Enzyme/Protease; Neuronal Signaling; Others
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Smiles
CS(=O)(NC1=CC=C(OC(CCCC)=C2C(C3=CC=C(OC([2H])([2H])C([2H])([2H])C([2H])([2H])N(CCCC)CCCC)C=C3)=O)C2=C1)=O
Molecular Formula
C31H38D6N2O5S
Molecular Weight
562.79
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216.|[2]Chinmay Patel, et al. Dronedarone. Circulation. 2009 Aug 18;120 (7) :636-44.|[3]Katarzyna M Sawicka, et al. Influence of dronedarone (a class III antiarrhythmic drug) on the anticonvulsant potency of four classical antiepileptic drugs in the tonic-clonic seizure model in mice. J Neural Transm (Vienna) . 2019 Feb;126 (2) :115-122.
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported

Related Products

CatalogName
HY-A0016-01Dronedarone
HY-75839-01Dronedarone (Hydrochloride)
HY-A0016R-01Dronedarone (Standard)
HY-75839R-01Dronedarone (Hydrochloride) (Standard)
HY-75572-01Dronedarone impurity 25 (hydrochloride)
HY-75572R-01Dronedarone impurity 25 (hydrochloride) (Standard)
HY-110225-01Levetiracetam-d6 (ring-d6)
HY-N0893STetrahydrocurcumin-d6
HY-W750155Tetramethrin-d6
HY-W744578Taurolidine-d6

Alternative Products

CatalogName
CS-EO-02951Dronedarone D6
CS-O-06569Dronedarone-d6 Fumarate
CS-O-03206Dronedarone-d6 Hydrochloride
EDC80923-01Dronedarone-d6 HCl
sc-362059Desbutyl Dronedarone-d6 HCl
TRC-D288878-1MGDesbutyl Dronedarone-d6 Hydrochloride
TMIH-0370-01N-Desbutyl Dronedarone-d6 HCl
MBS132011-01Dronedarone

Popular Products