Dronedarone (Hydrochloride) (Standard)

Dronedarone (Hydrochloride) (Standard)

• CAS Number: 141625-93-6
• UNSPSC Description: Dronedarone (Hydrochloride) (Standard) is the analytical standard of Dronedarone (Hydrochloride). This product is intended for research and analytical applications. Dronedarone Hydrochloride is a non-iodinated amiodarone derivative that inhibits Na+, K+ and Ca2+ currents.
• Target Antigen: Autophagy; Potassium Channel
• Type: Reference Standards
• Related Pathways: Autophagy;Membrane Transporter/Ion Channel
• Field of Research: Cardiovascular Disease
• Assay Protocol: https://www.medchemexpress.com/dronedarone-hydrochloride-standard.html
• Smiles: CS(=O)(NC1=CC=C(OC(CCCC)=C2C(C3=CC=C(OCCCN(CCCC)CCCC)C=C3)=O)C2=C1)=O.[H]Cl
• Molecular Weight: 593.22
• References & Citations: [1]Bogdan R, et al. Effect of?dronedarone?on Na+, Ca2+ and HCN channels. Naunyn Schmiedebergs Arch Pharmacol.?2011 Apr;383(4):347-56.?|[2]Doggrell SA, et al. Dronedarone: an amiodarone analogue. Expert Opin Investig Drugs. 2004 Apr;13(4):415-26.|[3]Manning AS, et al. SR 33589, a new amiodarone-like agent: effect on ischemia- and reperfusion-induced arrhythmias in anesthetized rats. J Cardiovasc Pharmacol. 1995 Sep;26(3):453-61.|[4]Breitenstein A, et al. Dronedarone reduces arterial thrombus formation. Basic Res Cardiol. 2012 Nov;107(6):302.
• Shipping Conditions: Room temperature
• Clinical Information: Launched