PROTAC Cbl-b-IN-1

PROTAC Cbl-b-IN-1

• CAS Number: 3035210-39-7
• UNSPSC Description: PROTAC Cbl-b-IN-1 (compound 64) is a PROTAC targeting Cbl-b. PROTAC Cbl-b-IN-1 is composed of PROTAC target protein ligand Cbl-b-IN-21 (HY-159615), PROTAC Linker Cbz-Pip-2C-Pip-C-Pip (HY-159617) and E3 ubiquitin ligase ligand (3S) Lenalidomide-5-Br (HY-W797329), where the E3 ubiquitin ligase ligand + Linker conjugate is (3S) Lenalidomide-5-Pip-C-Pip-2C-Pip (HY-159618)[1].
• Target Antigen: PROTACs
• Type: Reference compound
• Related Pathways: PROTAC
• Applications: Cancer-programmed cell death
• Field of Research: cancer
• Assay Protocol: https://www.medchemexpress.com/protac-cbl-b-in-1.html
• Smiles: OC=O.FC(F)(C1=CC(CN2CCN(CC2)CCN3CCC(CC3)CN4CCN(C5=CC=C(C(N([C@@H]6C(NC(CC6)=O)=O)C7)=O)C7=C5)CC4)=CN8C1=CN(C9=CC([C@H](C%10=NN=CN%10C)C%11CCC%11)=CC=C9)C8=O)F
• Molecular Weight: 1023.16
• References & Citations: [1]Preparation of imidazopyridine derivatives for treating disorders. World Intellectual Property Organization, WO2024077244 A1. 2024-04-11.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported