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PROTAC Cbl-b-IN-1

CAT: 0804-HY-159608Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-159608Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PROTAC Cbl-b-IN-1 (compound 64) is a PROTAC targeting Cbl-b. PROTAC Cbl-b-IN-1 is composed of PROTAC target protein ligand Cbl-b-IN-21 , PROTAC Linker Cbz-Pip-2C-Pip-C-Pip (HY-159617) and E3 ubiquitin ligase ligand (3S) Lenalidomide-5-Br (HY-W797329), where the E3 ubiquitin ligase ligand + Linker conjugate is (3S) Lenalidomide-5-Pip-C-Pip-2C-Pip (HY-159618).
CAS Number
3035210-39-7
UNSPSC
12352005
Target
PROTACs
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/protac-cbl-b-in-1.html
Smiles
OC=O.FC(F)(C1=CC(CN2CCN(CC2)CCN3CCC(CC3)CN4CCN(C5=CC=C(C(N([C@@H]6C(NC(CC6)=O)=O)C7)=O)C7=C5)CC4)=CN8C1=CN(C9=CC([C@H](C%10=NN=CN%10C)C%11CCC%11)=CC=C9)C8=O)F
Molecular Formula
C53H65F3N12O6
Molecular Weight
1023.16
References & Citations
[1]Preparation of imidazopyridine derivatives for treating disorders. World Intellectual Property Organization, WO2024077244 A1. 2024-04-11.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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