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PROTAC Cbl-b-IN-1

CAT: 0013-GTR19239191-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19239191-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PROTAC Cbl-b-IN-1 is a heterobifunctional degrader molecule designed to target the E3 ligase Cbl-b for proteasomal degradation. It consists of a Cbl-b ligand linked to a (3S) Lenalidomide-5-Br derivative, which recruits the CRBN E3 ubiquitin ligase. This compound is a valuable research tool for investigating Cbl-b's role in immune regulation and oncology in cellular studies.
CAS Number
3035210-39-7
Field of Research
Cancer Biology, Pharmacology & Drug Discovery
Smiles
C (O) =O.C (F) (F) (F) C=1C=2N (C (=O) N (C2) C3=CC ([C@@H] (C4CCC4) C=5N (C) C=NN5) =CC=C3) C=C (CN6CCN (CCN7CCC (CN8CCN (CC8) C=9C=C%10C (=CC9) C (=O) N (C%10) [C@@H]%11C (=O) NC (=O) CC%11) CC7) CC6) C1
Molecular Formula
C53H65F3N12O6
Molecular Weight
1023.16
Storage Conditions
-20°C
Notes
For research use only.

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