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IGS-1.76

CAT: 804-HY-122579-01Size: 5 mgDry Ice: NoHazardous: No
5 mgSelected
PRICE
AVAILABILITY
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
IGS-1.76 efficiently inhibits the human NCS-1/Ric8a complex. IGS-1.76 shows a significantly increased affinity for hNCS-1 and is able to modulate the hNCS-1/Ric8a interaction efficiently[1].
CAS Number
[313480-47-6]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Others
Type
Reference compound
Related Pathways
Others
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/igs-1-76.html
Concentration
10mM
Purity
98.57
Solubility
DMSO : 250 mg/mL (ultrasonic)
Smiles
O=C(NC1=NC2=CC=CC=C2S1)CC(C3=CC=CC=C3)C4=CC=CC=C4
Molecular Formula
C22H18N2OS
Molecular Weight
358.46
Precautions
H302, H315, H319, H335
References & Citations
[1]Carlos Roca, et al. Deciphering the Inhibition of the Neuronal Calcium Sensor 1 and the Guanine Exchange Factor Ric8a with a Small Phenothiazine Molecule for the Rational Generation of Therapeutic Synapse Function Regulators. J Med Chem. 2018 Jul 26;61 (14) :5910-5921.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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