Thymine-13C
CAT:
804-HY-W010450S3
Size:
1 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Thymine-13C
- CAS Number: 200417-68-1
- UNSPSC Description: Thymine-13C is the 13C labeled Thymine[1]. Thymine is one of the four nucleobases in the nucleic acid of DNA and can be a target for actions of 5-fluorouracil (5-FU) in cancer treatment, with a Km of 2.3 μM[2].
- Target Antigen: Endogenous Metabolite
- Type: Isotope-Labeled Compounds
- Related Pathways: Metabolic Enzyme/Protease
- Applications: Metabolism-protein/nucleotide metabolism
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/thymine-13c.html
- Solubility: 10 mM in DMSO
- Smiles: O=C1C([13CH3])=CNC(N1)=O
- Molecular Weight: 127.11
- References & Citations: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.|[2]Tuchman M, et al. Effects of uridine and thymidine on the degradation of 5-fluorouracil, uracil, and thymine by rat liver dihydropyrimidine dehydrogenase. Cancer Res. 1985 Nov;45(11 Pt 1):5553-6.
- Shipping Conditions: Room temperature
- Clinical Information: No Development Reported