Thymine-15N2,13C

• Description:

  Thymine-15N2,13C is the 13C and 15N labeled Thymine (HY-W010450) . Thymine is one of the four nucleobases in the nucleic acid of DNA and can be a target for actions of 5-Fluorouracil (HY-90006) in cancer treatment, with a Km of 2.3 μM[1].

• UNSPSC:

  12352005

• Hazard Statement:

  H319

• Target:

  Endogenous Metabolite; Isotope-Labeled Compounds

• Related Pathways:

  Metabolic Enzyme/Protease; Others

• Field of Research:

  Cancer

• Purity:

  99.90

• Smiles:

  O=C([15N](C1=O)[H])C([13CH3])=C[15N]1[H]

• Molecular Formula:

  C4 13CH6 15N2O2

• Molecular Weight:

  129.09

• Precautions:

  H319

• References & Citations:

  [1]Tuchman M, et al. Effects of uridine and thymidine on the degradation of 5-fluorouracil, uracil, and thymine by rat liver dihydropyrimidine dehydrogenase. Cancer Res. 1985 Nov;45 (11 Pt 1) :5553-6.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category:

  Isotope-Labeled Compounds

• Clinical Information:

  No Development Reported