Thymine

• UNSPSC Description:

  Thymine is one of the four nucleobases in the nucleic acid of DNA and can be a target for actions of 5-fluorouracil (5-FU) in cancer treatment, with a Km of 2.3 μM.

• Target Antigen:

  Endogenous Metabolite

• Type:

  Natural Products

• Related Pathways:

  Metabolic Enzyme/Protease

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer; Metabolic Disease

• Assay Protocol:

  https://www.medchemexpress.com/5-Methylpyrimidine-2,4_1H,3H_-dione.html

• Purity:

  99.98

• Solubility:

  DMSO : 100 mg/mL (ultrasonic)|H2O : 5 mg/mL (ultrasonic)

• Smiles:

  O=C1NC(C(C)=CN1)=O

• Molecular Weight:

  126.11

• References & Citations:

  [1]Tuchman M, et al. Effects of uridine and thymidine on the degradation of 5-fluorouracil, uracil, and thymine by rat liver dihydropyrimidine dehydrogenase. Cancer Res. 1985 Nov;45(11 Pt 1):5553-6.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Clinical Information:

  No Development Reported

• CAS Number:

  65-71-4