Recombinant Rat Siglec-2/CD22 Protein

• Description:

  Recombinant Rat Siglec-2/CD22 Protein_x000D_ Catalog number: B2019221_x000D_ Lot number: Batch Dependent_x000D_ Expiration Date: Batch dependent_x000D_ Amount: 50 µg_x000D_ Molecular Weight or Concentration: 76.7 kDa_x000D_ Supplied as: Powder_x000D_ Applications: a molecular tool for various biochemical applications_x000D_ Storage: -20°C_x000D_ Keywords: Recombinant Rat Siglec-2/CD22 Protein (ECD, His Tag)_x000D_ Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ References:_x000D_ 1: Bakker TR, Piperi C, Davies EA, Merwe PA. Comparison of CD22 binding to native CD45 and synthetic oligosaccharide Eur J Immunol. 2002 Jul;32(7):1924-32._x000D_ 2: van der Merwe PA, Crocker PR, Vinson M, Barclay AN, Schauer R, Kelm S. Localization of the putative sialic acid-binding site on the immunoglobulin superfamily cell-surface molecule CD22 J Biol Chem. 1996 Apr 19;271(16):9273-80._x000D_ 3: Keppler OT, Hinderlich S, Langner J, Schwartz-Albiez R, Reutter W, Pawlita M. UDP-GlcNAc 2-epimerase: a regulator of cell surface sialylation Science. 1999 May 21;284(5418):1372-6._x000D_ 4: Alderson RF, Kreitman RJ, Chen T, Yeung P, Herbst R, Fox JA, Pastan I. CAT-8015: a second-generation pseudomonas exotoxin A-based immunotherapy targeting CD22-expressing hematologic malignancies Clin Cancer Res. 2009 Feb 1;15(3):832-9._x000D_ 5: Nath D, van der Merwe PA, Kelm S, Bradfield P, Crocker PR. The amino-terminal immunoglobulin-like domain of sialoadhesin contains the sialic acid binding site. Comparison with CD22 J Biol Chem. 1995 Nov 3;270(44):26184-91._x000D_ 6: Sgroi D, Nocks A, Stamenkovic I. A single N-linked glycosylation site is implicated in the regulation of ligand recognition by the I-type lectins CD22 and CD33 J Biol Chem. 1996 Aug 2;271(31):18803-9._x000D_ 7: Zammarchi F, Havenith KE, Sachini N, Janghra N, Chivers S, Idusogie E, Gaudio E, Tarantelli C, Bertelli F, Santos K, Tyrer P, Corbett S, Spriano F, Golino G, Cascione L, Bertoni F, Hartley JA, van Berkel PH. ADCT-602, a Novel PBD Dimer-containing Antibody-Drug Conjugate for Treating CD22-positive Hematologic Malignancies Mol Cancer Ther. 2024 Apr 2;23(4):520-531._x000D_ 8: Law CL, Torres RM, Sundberg HA, Parkhouse RM, Brannan CI, Copeland NG, Jenkins NA, Clark EA. Organization of the murine Cd22 locus. Mapping to chromosome 7 and characterization of two alleles J Immunol. 1993 Jul 1;151(1):175-87._x000D_ 9: Sawzdargo M, George SR, Nguyen T, Xu S, Kolakowski LF, O'Dowd BF. A cluster of four novel human G protein-coupled receptor genes occurring in close proximity to CD22 gene on chromosome 19q13.1 Biochem Biophys Res Commun. 1997 Oct 20;239(2):543-7._x000D_ 10: Fujino Y, Li Q, Chung H, Hikita N, Nussenblatt RB, Gery I, Chan CC. Immunopathology of experimental autoimmune uveoretinitis in primates Autoimmunity. 1992;13(4):303-9. _x000D_ _x000D_ Products Related to Recombinant Rat Siglec-2/CD22 Protein can be found at Proteins

• Short Description:

  Catalog Number: B2019221 (50 µg)_x000D_ Recombinant Rat Siglec-2/CD22 Protein is a laboratory-produced protein derived from rat CD22. This protein is significant for research in immune response and B cell biology. This product has been used as a molecular tool for various biochemical applications. It has also been used in a wide array of other chemical and immunological applications. Custom bulk amounts of this product are available upon request._x000D_ _x000D_

• Weight:

  0.15

• Length:

  2

• Width:

  0.5

• Height :

  0.5

• CAS Number:

  9000-83-3