Recombinant Mouse Siglec-2/CD22 Protein

• Description:

  Recombinant Mouse Siglec-2/CD22 Protein_x000D_ Catalog number: B2019191_x000D_ Lot number: Batch Dependent_x000D_ Expiration Date: Batch dependent_x000D_ Amount: 50 µg_x000D_ Molecular Weight or Concentration: 78.8 kDa_x000D_ Supplied as: Powder_x000D_ Applications: a molecular tool for various biochemical applications_x000D_ Storage: -20°C_x000D_ Keywords: A530093D23 Protein, Mouse; Cd22 Protein, Mouse; Lyb-8 Protein, Mouse; Lyb8 Protein, Mouse; Siglec2 Protein, Mouse_x000D_ Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ References:_x000D_ 1: Bera TK, Onda M, Kreitman RJ, Pastan I. An improved recombinant Fab-immunotoxin targeting CD22 expressing malignancies Leuk Res. 2014 Oct;38(10):1224-9._x000D_ 2: Vallera DA, Todhunter DA, Kuroki DW, Shu Y, Sicheneder A, Chen H. A bispecific recombinant immunotoxin, DT2219, targeting human CD19 and CD22 receptors in a mouse xenograft model of B-cell leukemia/lymphoma Clin Cancer Res. 2005 May 15;11(10):3879-88._x000D_ 3: Nikolova KA, Mihaylova NM, Voynova EN, Tchorbanov AI, Voll RE, Vassilev TL. Selective silencing of autoreactive B lymphocytes-Following the Nature's way Autoimmun Rev. 2010 Sep;9(11):775-9._x000D_ 4: Sathish JG, Walters J, Luo JC, Johnson KG, Leroy FG, Brennan P, Kim KP, Gygi SP, Neel BG, Matthews RJ. CD22 is a functional ligand for SH2 domain-containing protein-tyrosine phosphatase-1 in primary T cells J Biol Chem. 2004 Nov 12;279(46):47783-91._x000D_ 5: Haso W, Lee DW, Shah NN, Stetler-Stevenson M, Yuan CM, Pastan IH, Dimitrov DS, Morgan RA, FitzGerald DJ, Barrett DM, Wayne AS, Mackall CL, Orentas RJ. Anti-CD22-chimeric antigen receptors targeting B-cell precursor acute lymphoblastic leukemia Blood. 2013 Feb 14;121(7):1165-74._x000D_ 6: Cao A, Alluqmani N, Buhari FHM, Wasim L, Smith LK, Quaile AT, Shannon M, Hakim Z, Furmli H, Owen DM, Savchenko A, Treanor B. Galectin-9 binds IgM-BCR to regulate B cell signaling Nat Commun. 2018 Aug 17;9(1):3288._x000D_ 7: Newton DL, Stockwin LH, Rybak SM. Anti-CD22 Onconase: preparation and characterization Methods Mol Biol. 2009;525:425-43, xiv._x000D_ 8: Toda M, Akita K, Inoue M, Taketani S, Nakada H. Down-modulation of B cell signal transduction by ligation of mucins to CD22 Biochem Biophys Res Commun. 2008 Jul 18;372(1):45-50._x000D_ 9: John B, Herrin BR, Raman C, Wang YN, Bobbitt KR, Brody BA, Justement LB. The B cell coreceptor CD22 associates with AP50, a clathrin-coated pit adapter protein, via tyrosine-dependent interaction J Immunol. 2003 Apr 1;170(7):3534-43._x000D_ 10: Doody GM, Justement LB, Delibrias CC, Matthews RJ, Lin J, Thomas ML, Fearon DT. A role in B cell activation for CD22 and the protein tyrosine phosphatase SHP Science. 1995 Jul 14;269(5221):242-4. _x000D_ _x000D_ Products Related to Recombinant Mouse Siglec-2/CD22 Protein can be found at Proteins

• Short Description:

  Catalog Number: B2019191 (50 µg)

• Weight:

  0.15

• Length:

  2

• Width:

  0.5

• Height:

  0.5

• Height :

  0.5

• CAS Number:

  9000-83-3