Recombinant Human Siglec-3/CD33 Protein (ECD, His Tag)

• Description:

  Recombinant Human Siglec-3/CD33 Protein (ECD, His Tag)_x000D_ Catalog number: B2019153_x000D_ Lot number: Batch Dependent_x000D_ Expiration Date: Batch dependent_x000D_ Amount: 50 µg_x000D_ Molecular Weight or Concentration: 28.2 kDa_x000D_ Supplied as: Powder_x000D_ Applications: a molecular tool for various biochemical applications_x000D_ Storage: −20°C_x000D_ Keywords: CD33rSiglec Protein, Human; FLJ00391 Protein, Human; p67 Protein, Human; SIGLEC-3 Protein, Human; SIGLEC3 Protein, Human_x000D_ Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ References:_x000D_ 1: Brinkman-Van der Linden EC, Angata T, Reynolds SA, Powell LD, Hedrick SM, Varki A. CD33/Siglec-3 binding specificity, expression pattern, and consequences of gene deletion in mice Mol Cell Biol. 2003 Jun;23(12):4199-206._x000D_ 2: Wang H, Liu H, Wang A, Zhen J, Wu X, Chen M, Gong M, Qu H, Zhou S, Tao X, Liao X. [Preparation of monoclonal antibody against human CD33 by immunizing mice with recombinant vector] Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi. 2020 Feb;36(2):169-174._x000D_ 3: Angata T, Hingorani R, Varki NM, Varki A. Cloning and characterization of a novel mouse Siglec, mSiglec-F: differential evolution of the mouse and human (CD33) Siglec-3-related gene clusters J Biol Chem. 2001 Nov 30;276(48):45128-36._x000D_ 4: Verfaillie CM, Miller JS. CD34+/CD33- cells reselected from macrophage inflammatory protein 1 alpha+interleukin-3--supplemented "stroma-noncontact" cultures are highly enriched for long-term bone marrow culture initiating cells Blood. 1994 Sep 1;84(5):1442-9._x000D_ 5: Lemoli RM, Fogli M, Fortuna A, Motta MR, Rizzi S, Benini C, Tura S. Interleukin-11 stimulates the proliferation of human hematopoietic CD34+ and CD34+CD33-DR- cells and synergizes with stem cell factor, interleukin-3, and granulocyte-macrophage colony-stimulating factor Exp Hematol. 1993 Dec;21(13):1668-72._x000D_ 6: Wong E, Malviya M, Jain T, Liao GP, Kehs Z, Chang JC, Studer L, Scheinberg DA, Li YM. HuM195 and its single-chain variable fragment increase Aβ phagocytosis in microglia via elimination of CD33 inhibitory signaling Mol Psychiatry. 2024 Jul;29(7):2084-2094._x000D_ 7: Patel N, Brinkman-Van der Linden EC, Altmann SW, Gish K, Balasubramanian S, Timans JC, Peterson D, Bell MP, Bazan JF, Varki A, Kastelein RA. OB-BP1/Siglec-6. a leptin- and sialic acid-binding protein of the immunoglobulin superfamily J Biol Chem. 1999 Aug 6;274(32):22729-38._x000D_ 8: Floyd H, Ni J, Cornish AL, Zeng Z, Liu D, Carter KC, Steel J, Crocker PR. Siglec-8. A novel eosinophil-specific member of the immunoglobulin superfamily J Biol Chem. 2000 Jan 14;275(2):861-6._x000D_ 9: Angata T, Kerr SC, Greaves DR, Varki NM, Crocker PR, Varki A. Cloning and characterization of human Siglec-11. A recently evolved signaling molecule that can interact with SHP-1 and SHP-2 and is expressed by tissue macrophages, including brain microglia J Biol Chem. 2002 Jul 5;277(27):24466-74._x000D_ 10: Whitney G, Wang S, Chang H, Cheng KY, Lu P, Zhou XD, Yang WP, McKinnon M, Longphre M. A new siglec family member, siglec-10, is expressed in cells of the immune system and has signaling properties similar to CD33 Eur J Biochem. 2001 Dec;268(23):6083-96. _x000D_ _x000D_ Products Related to Recombinant Human Siglec-3/CD33 Protein (ECD, His Tag) can be found at Proteins

• Short Description:

  Catalog Number: B2019153 (50 µg)

• Weight:

  0.15

• Length:

  2

• Width:

  0.5

• Height:

  0.5

• Height :

  0.5

• CAS Number:

  9000-83-3