Amiodarone Hydrochloride

• Background:

  Amiodarone is a non-selective ion channel blocker. It has been found, when used in Saccharomyces cerevisiae, to induce an influx of Ca2+ followed by mitochondrial fragmentation and subsequent cell death. Amiodarone has also been shown to induce autophagy by inhibiting mTORC1. Lastly, Amiodarone has broad-spectrum fungicidal activity.

• Description:

  Autophagy inducer

• Product Name Alternative:

  2-Butyl-3-benzofuranyl-4-[2-(diethylamino)ethoxy]-3,5-diiodophenyl ketone hydrochloride

• UNSPSC:

  41116105

• Source:

  Synthetic

• Purity:

  >99 %

• Weight:

  1

• Format:

  White solid

• Solubility:

  Soluble to 50 mM in DMSO

• Molecular Formula:

  C25H29I2NO3•HCl

• Molecular Weight:

  681.77

• Precautions:

  Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

• References & Citations:

  1. Zhang Y., et al. (2007). J Biol Chem. 282(52): 37844-53. 2. Balgi A., et al. (2009). PLoS One. 4(9): e7124.

• CAS Number:

  19774-82-4