Amiodarone Hydrochloride

CAT: 0400-SIH-393-1GSize: 1 gDry Ice: NoHazardous: No
CAT#:0400-SIH-393-1GSize:1 g
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Background
Amiodarone is a non-selective ion channel blocker. It has been found, when used in Saccharomyces cerevisiae, to induce an influx of Ca2+ followed by mitochondrial fragmentation and subsequent cell death. Amiodarone has also been shown to induce autophagy by inhibiting mTORC1. Lastly, Amiodarone has broad-spectrum fungicidal activity.
Description
Autophagy inducer
CAS Number
19774-82-4
Product Name Alternative
2-Butyl-3-benzofuranyl-4-[2- (diethylamino) ethoxy]-3,5-diiodophenyl ketone hydrochloride
UNSPSC
41116105
Type
Inducer
Source
Synthetic
Field of Research
Cancer | Autophagy
Purity
>99 %
Weight
1
Format
White solid
Solubility
Soluble to 50 mM in DMSO
Molecular Formula
C25H29I2NO3•HCl
Molecular Weight
681.77
Precautions
Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
References & Citations
1. Zhang Y., et al. (2007). J Biol Chem. 282(52): 37844-53. 2. Balgi A., et al. (2009). PLoS One. 4(9): e7124.

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