GSK690693 Hydrochloride

• Background:

  GSK690693 Hydrochloride is an ATP-competitive pan-Akt kinase inhibitor. It is derived from aminofurazan. It has shown to produce antiproliferative and apoptotic effects in tumor cell lines.

• Description:

  AKT kinase inhibitor

• Product Name Alternative:

  4-[2- (4-Amino-1,2,5-oxadiazol-3-yl) -1-ethyl-7-[ (3S) -3-piperidinylmethoxy) -1H-imidazo[4,5-c]pyridin-4-yl]-2-methyl-3-butyn-2-ol

• UNSPSC:

  41116105

• Type:

  Inhibitor

• Source:

  Synthetic

• Field of Research:

  Cell Signaling | Cancer | Apoptosis | Cancer Growth Inhibitors | Tyrosine Kinase Inhibitors

• Purity:

  ≥98% (HPLC)

• Weight:

  0.005

• Format:

  White to beige solid

• Solubility:

  Soluble to 50 mM in DMSO

• Molecular Formula:

  C21H27N7O3

• Molecular Weight:

  425.5

• Precautions:

  Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

• References & Citations:

  1. Heerding D.A., et al. (2008) J. Med. Chem. 51(18): 5663–5679. 2. Rhodes N., et al. (2008) Cancer Res. 68(7): 2366–2374.

• CAS Number:

  937174-76-0